AL 082D06游离态
AL 082D06(AL 082D06)
CAS: 256925-03-8
化学式: C23H24ClN3O2
| 中文名 | AL 082D06 |
| 英文名 | AL 082D06 |
| 别名 | 化合物AL082D06 AL 082D06游离态 4,4'-((2-氯-5-硝基苯基)亚甲基)双(N,N-二甲基苯胺) |
| 英文别名 | D 06 D06 D-06 AL082D06 AL-082D06 AL 082D06 AL 082D06(D-06) 4,4'-[(2-Chloro-5-nitrophenyl)methylene]bis[N,N-dimethylbenzenamine] 4-[(2-Chloro-5-nitrophenyl)-[4-(dimethylamino)phenyl]methyl]-N,N-dimethylaniline |
| CAS | 256925-03-8 |
| 化学式 | C23H24ClN3O2 |
| 分子量 | 409.91 |
| 密度 | 1.232±0.06 g/cm3(Predicted) |
| 沸点 | 543.7±50.0 °C(Predicted) |
| 溶解度 | DMSO: 7.5 mg/mL |
| 酸度系数 | 5.36±0.24(Predicted) |
| 存储条件 | 2-8°C |
| 体外研究 | AL 082D06 (D06) binds specifically to GR with nanomolar affinity. Addition of AL 082D06 causes a dose-dependent decrease in transcriptional activation from the MMTV:Luc reporter stimulated with half-maximal DEX concentrations. AL 082D06 acts to antagonize reporter activity using several glucocorticoid-responsive promoter- reporter systems including the 3-kb tyrosine amino transferase (TAT) promoter and less complex promoters comprised of isolated glucocorticoid response element (GRE) sequences. AL 082D06 competes with 3 H-Dex for baculovirus-expressed GR with nanomolar affinity. Other intracellular receptors (AR, ER, PR, and MR) have no affinity for AL 082D06 in a similarly structured binding assay with the appropriate receptor and tritiated ligand (>2500 nM). AL 082D06 has no activation efficacy on the progesterone, androgen, mineralocorticoid, retinoid, glucocorticoid, or estrogen receptors. AL 082D06 is very efficacious at antagonizing GR activity but exhibits much weaker efficacy when tested against the other steroid receptors in contrast to the reference antagonists used as controls. |
AL 082D06游离态 - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.44 ml | 12.198 ml | 24.396 ml |
| 5 mM | 0.488 ml | 2.44 ml | 4.879 ml |
| 10 mM | 0.244 ml | 1.22 ml | 2.44 ml |
| 5 mM | 0.049 ml | 0.244 ml | 0.488 ml |
最后更新：2024-01-02 23:10:35
AL 082D06游离态 - 简介
AL 082D06是一种化合物，它的性质是属于无机化合物。
最后更新：2024-04-10 22:29:15
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提供多种规格现货供应
产品名: AL 082D06游离态 去供应商网站查看 询盘CAS: 256925-03-8
产地: 北京
包装: 瓶
规格: YS142367-10mg,YS142367-25mg,YS142367-100mg,YS142367-50mg,YS142367-250mg,YS142367-5mg
价格: 电话、微信、QQ、邮件
库存: 一周左右
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销，欢迎来询
现货供应
产品名: AL 082D06游离态 去供应商网站查看 询盘CAS: 256925-03-8
产地: 中国上海
包装: 10mg
规格: 98%
价格: 79.00
库存: 现货
电话: 400-900-4166
手机: 18017137653
电子邮件: 3007523013@qq.com
QQ: 3007523013
微信: 18017137653
产品描述: 中文名：AL 082D06游离态 英文名:AL 082D06 CAS:256925-03-8 规格:98% 产地:中国上海
提供多种规格现货供应
产品名: AL 082D06游离态 去供应商网站查看 询盘CAS: 256925-03-8
产地: 北京
包装: 瓶
规格: YS142367-10mg,YS142367-25mg,YS142367-100mg,YS142367-50mg,YS142367-250mg,YS142367-5mg
价格: 电话、微信、QQ、邮件
库存: 一周左右
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销，欢迎来询
现货供应
产品名: AL 082D06游离态 去供应商网站查看 询盘CAS: 256925-03-8
产地: 中国上海
包装: 10mg
规格: 98%
价格: 79.00
库存: 现货
电话: 400-900-4166
手机: 18017137653
电子邮件: 3007523013@qq.com
QQ: 3007523013
微信: 18017137653
产品描述: 中文名：AL 082D06游离态 英文名:AL 082D06 CAS:256925-03-8 规格:98% 产地:中国上海
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